For a long time, the umbilical cord was considered a labor surplus, but currently is seen as a major source of stem cells with high therapeutic potential. In addition to the blood that you can collect from the umbilical cord, and currently is used in the treatment of more than 80 diseases – from diseases of blood-cancer Forum the metabolic and immune system diseases – also the very fabric of the umbilical cord, which surrounds the blood vessels in your interior, Rico is stem cell research. These cells have potential different from that found in blood, having the ability to give rise to cells of different tissues.
What Are Mesenchymal Stem Cells?
The tissue of the umbilical cord is Rico in what is referred to as mesenchymal stem cells. These cells are able to cause muscle cells, bone, cartilage and fat, and have the ability to adjust the response of the immune system, and may therefore have an important role in the treatment of autoimmune diseases such as type 1 diabetes and lupus, among others. Currently, these cells are already used in co-transplante with hematopoietic stem cells (from umbilical cord blood, peripheral blood or bone marrow), in order to help reduce the complications associated with transplants and increase the likelihood of success.
Clinical Trials with Mesenchymal Cells From Umbilical Cord Tissue
Compared with cells from umbilical cord blood, the clinical interest in mesenchymal stem cells took place later but, despite this, at the moment the number of ongoing clinical trials with mesenchymal cells from umbilical cord tissue – for evaluation of your potential in treatment of several diseases – is considerable. Currently, are being tested in diseases such as diabetes, ulcerative colitis, liver cirrhosis, cardiomyopathies, amyotrophic lateral sclerosis, multiple sclerosis, lupus, rheumatoid arthritis, graft-versus-host disease, cerebral palsy, autism, muscular dystrophy and Alzheimer’s disease, among others.
Main Features of Mesenchymal Cells
Despite the mesenchymal stem cells be able to obtain from other sources, such as the bone marrow and adipose tissue, the tissue of the umbilical cord presents some advantages when compared with other sources. To your harvest is simple, painless and risk-free (for the mother and the baby); because they are very primitive, these cells have a higher potential for differentiation and proliferation; and have a lower risk of infection by bacteria and viruses.
The use of stem cells in clinical practice, particularly mesenchymal stem cells, has increased considerably in the last decade. During this time, the scientific community has tried to understand their mechanisms of action in the repair and regeneration of tissues and demonstrate your potential on cell therapy and regenerative medicine.
The potential they present, mesenchymal stem cells represent one of the greatest hopes of regenerative medicine, being expected to contribute to the treatment of diseases for which there is still no effective therapy.